Key result
Novel OSCOC metric outperforms standard concordance measures for detecting nonlinear atrial arrhythmias.
Why the study?
A novel concordance coefficient is needed to better quantify association among multichannel biosignals, including cardiac signals for arrhythmia analysis.
The proposed OSCOC metric provides a robust method for quantifying associations in multichannel biosignals, demonstrating superior performance in analyzing complex nonlinear data such as atrial arrhythmias.
OSCOC may aid multichannel biosignal analysis in research; leaves open clinical validation before any practice adoption.
In this paper, we propose a novel concordance coefficient, called order statistics concordance coefficient (OSCOC), to quantify the association among multichannel biosignals. To uncover its properties, we compare OSCOC with three other similar indexes, i.e., average Pearson's product moment correlation coefficient (APPMCC), Kendall's concordance coefficients (KCC), and average Kendall's tau (AKT), under a multivariate normal model (MNM), linear model (LM), and nonlinear model. To further demonstrate its usefulness, we present an example on atrial arrhythmia analysis based on real-world multichannel cardiac signals. Theoretical derivations as well as numerical results suggest that 1) under MNM and LM, OSCOC performs equally well with APPMCC, and outperforms the other two methods, 2) in nonlinear case, OSCOC even has better performance than KCC and AKT, which are well known to be robust under increasing nonlinear transformations, and 3) OSCOC performs the best in the case study of arrhythmia analysis in terms of the volume under the surface.
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Xu et al. (2016) studied Atrial arrhythmia. Order statistics concordance coefficient (OSCOC) vs. APPMCC, KCC, and AKT was evaluated on Performance in quantifying association among multichannel biosignals. The proposed order statistics concordance coefficient (OSCOC) outperformed APPMCC, KCC, and AKT in nonlinear cases and real-world atrial arrhythmia analysis.
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