Key result
In healthy young Japanese females consuming identical meals, the peak postprandial interstitial fluid glucose level was lowest after breakfast (118 mg/dL), followed by lunch (137 mg/dL), and highest after dinner (155 mg/dL) (p<0.05).
Why the study?
Does meal timing affect postprandial interstitial fluid glucose levels in healthy young females?
Does meal timing affect postprandial interstitial fluid glucose levels in healthy young females?
Meal timing significantly impacts postprandial glucose fluctuations, with breakfast resulting in the lowest glucose peaks and AUC compared to lunch and dinner in healthy young females.
Small study of healthy young women limits immediate clinical use of mealtime glucose data; leaves open generalizability and need for larger confirmatory trials.
Flash glucose monitoring (FGM) provides continuous and accessible measurement of the interstitial fluid glucose (ISFG) level and this system is useful for understanding blood glucose fluctuations. We examined differences in postprandial ISFG after the main mealtimes (breakfast, lunch, and dinner) in healthy young Japanese females. Nine healthy young females (aged 21.5±0.6 y old) were enrolled in this study. ISFG was continuously measured by FGM. Participants ate the same meal three times a day consecutively, thereby satisfying their daily energy requirements. Postprandial ISFG fluctuations were evaluated for 4 h after each meal. There were no significant differences in ISFG before the 3 main meals. The postprandial ISFG peak was the lowest after breakfast, increasing in the order of lunch and then dinner. The area under the curve of the 4-h postprandial ISFG was higher after lunch and dinner than after breakfast. The results of this study suggest that postprandial ISFG differ depending on mealtimes in young Japanese females.
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Takahashi et al. (2020) studied Healthy (n=9). Meal timing (breakfast, lunch, dinner) vs. Within-subject comparison across mealtimes was evaluated on Peak postprandial interstitial fluid glucose (ISFG) value (p=<0.05). In healthy young Japanese females consuming identical meals, the peak postprandial interstitial fluid glucose level was lowest after breakfast (118 mg/dL), followed by lunch (137 mg/dL), and highest after dinner (155 mg/dL) (p<0.05).
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