Clinical Recognition of Clear-Cell Acanthoma (Degos')

We are reporting four additional patients with typical Degos' clear-cell acanthomas to emphasize that a clinical diagnosis is possible. A single, 1- or 2-cm, slowly growing, domeshaped, sharply delineated, erythematous, usually smooth papule, stippled with tiny red puncta which blanche on pressure and marginated by a thin keratinous scale, suggests the diagnosis. Presurgical recognition may avert unnecessary radical treatment.