Endovascular Therapy for Ischemic Stroke

To the Editor: In their report on the Extending the Time for Thrombolysis in Emergency Neurological Deficits — Intra-Arterial (EXTEND-IA) trial, Campbell et al. (March 12 issue)1 suggest that in MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands), local investigators might have selected patients on the basis of findings on computed tomographic (CT) perfusion imaging, although such selection was not specified in the protocol.2,3 We compared the effect of endovascular therapy in patients with and in those without CT perfusion data. In 166 patients without such data, the adjusted common odds . . .