Key result
Male pattern baldness fails to independently predict angiographic CAD severity after adjusting for age.
Why the study?
The association between male pattern baldness and angiographic coronary artery disease severity and collateral development had not been previously reported.
Does male pattern baldness predict angiographic coronary artery disease severity and collateral development in male patients?
Cross-Sectional (n=511)
Blinded observers
No
Does male pattern baldness predict angiographic coronary artery disease severity and collateral development in male patients?
Male pattern baldness is not independently associated with angiographic coronary artery disease severity or collateral development.
Does not support using male pattern baldness for CAD risk assessment; leaves open age-independent links for prospective study.
OBJECTIVE: We aimed to investigate whether there is an association between male pattern baldness and angiographic coronary artery disease (CAD) severity and collateral development, which has not been reported previously. METHODS: Coronary arteriograms, CAD risk factors, lipid parameters and presence and severity of baldness in 511 male patients were prospectively evaluated. Baldness was classified into five groups. Severity of CAD was evaluated with the Gensini scoring system and collateral development with Rentrop scores. RESULTS: Although subjects with a higher Gensini score had more frequent and severe baldness, they were older than the group with lower Gensini scores. Bald patients had a higher Gensini score when compared with their non-bald counterparts. In univariate analysis, age more than 60, body mass index more than 30, smoking and baldness were predictors of high Gensini scores. In multivariate analysis, only age more than 60, body mass index more than 30 and smoking were independent predictors of a high Gensini score. There were no differences in terms of presence and severity of baldness in subjects with and without adequate collateral development. CONCLUSIONS: There was no relation between presence, severity and age of occurrence of male pattern baldness and Gensini and Rentrop scores, which are important measures of presence and severity of CAD.
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Sarı et al. (2015) conducted a cross-sectional in Coronary artery disease (n=511). Male pattern baldness vs. Non-bald patients was evaluated on Mean Gensini score (p=0.003). Male pattern baldness was associated with higher unadjusted Gensini scores, but was not an independent predictor of angiographic coronary artery disease severity after adjusting for age.
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