Key result
Young male patients with coronary heart disease had higher rates of smoking, family history, and single-vessel disease, but lower rates of myocardial infarction and multivessel disease compared to middle-aged patients.
Why the study?
The incidence of coronary heart disease is increasing annually with more young patients, but the coronary artery and clinical features in young and middle-aged male patients are not well characterized.
Observational (n=110)
No
Young male patients with CHD present with a distinct clinical profile characterized by a higher burden of traditional metabolic risk factors but less complex, predominantly single-vessel coronary anatomy compared to middle-aged men.
Distinct risk profiles in young men with CHD may guide targeted prevention; hypothesis-generating and should not yet change practice.
BACKGROUNDCoronary heart disease (CHD) is a type of coronary atherosclerotic heart disease.In recent years, the incidence of CHD has been increasing annually, with an increasing number of young patients.Severe CHD may cause severe myocardial ischemia or myocardial necrosis, which in turn may cause myocardial infarction and related complications that seriously affect the life and health of the patient. AIMTo examine the coronary arteries and clinical features of young and middle-aged male patients with CHD. METHODSFrom February 2019 to January 2020, 110 male CHD patients admitted to our hospital were selected as research subjects and were divided into two groups by age: middle-aged group (n = 55) and young group (n = 55).The coronary arteries and clinical features of the patients were compared. RESULTSThere were no significant differences in dyslipidemia, stroke history, high-density lipoprotein cholesterol, or triacylglycerol (P > 0.05) between the two groups.In the young group, age, diabetes, hypertension, smoking history, body mass index, family history of CHD, drinking history, fibrinogen, low-density lipoprotein cholesterol, total cholesterol, and single-vessel disease were higher than those in the middle-aged group.Correspondingly, serum uric acid, hyperuricemia, myocardial infarction, Gensini score > 50, collateral circulation, multivessel disease, double vessel disease, involvement of the right coronary artery, and involvement of the left main coronary artery were lower in the young group than Peng KG et al.CHD and CRD in young and middle-aged men WJCC https://www.wjgnet.
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Peng et al. (2021) conducted an observational in Coronary heart disease (n=110). Young age vs. Middle age was evaluated on Coronary arteries and clinical features. Young male patients with coronary heart disease had higher rates of smoking, family history, and single-vessel disease, but lower rates of myocardial infarction and multivessel disease compared to middle-aged patients.
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