Sixteen parkinsonians with acquired drug-resistant "off" periods without dyskinesia were placed on a diet in which virtually all protein was concentrated in the evening meal. Restoration of sensitivity to levodopa resulted in 88%. Ten patients (62%) have continued to comply with the diet for 7 months (mean). Two patients were studied in detail. Immobility correlated with elevated plasma levels of large neutral amino acids (LNAA), normality with low LNAA.
No takes yet. Share an insight, caveat, or question.
Pincus et al. (1988) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context:
More from Neurology