Antimalarial principles of Spathodea campanulata stem bark extract were isolated and characterized. The antimalarial principles in the stem bark were 3β-hydroxyurs-12-en-28-oic acid (ursolic acid) and two of its derivatives; 3β-hydroxyurs-12,19-dien-28-oic acid (tomentosolic acid) and 3β,20β-dihydroxyurs-12-en-28 oic acid. This is the first report of the isolation of ursolic acid and its derivatives as antimalarial compounds
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Amusan et al. (1996) studied this question.
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