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Vitamin E is the most important tissue antioxidant in preventing or controlling non‐specific reactions from various oxidizing species produced in normal metabolism. Through this action, the vitamin protects polyunsaturated fatty acid loss from phospholipids and consequent membrane damage. The U.S. diet has an abundance of vitamin E and normal individuals accumulate effective amounts in their tissues, which is consistent with the latest recommended dietary allowances for vitamin E as indicated by the National Research Council.
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John G. Bieri (1984) studied this question.
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