Laboratory Validation of Xpert Chlamydia trachomatis/Neisseria gonorrhoeae and Trichomonas vaginalis Testing as Performed by Nurses at Three Primary Health Care Facilities in South Africa

The introduction of molecular diagnostic tests provides an important step to address the burden of sexually transmitted infections (STIs), especially Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis. Recently developed Xpert CT/NG (for C. trachomatis/N. gonorrhoeae) and TV (for T. vaginalis) assays provide opportunities to detect these STIs in resource-limited settings. When performed by staff at primary health care (PHC) facilities, patients can be provided results and treatment within 2 h.