Why the study?
Atrial fibrillation is the most common cardiac arrhythmia worldwide, but detailed sociodemographic and clinical characteristics in Colombian patients were not well described.
What are the sociodemographic and clinical features, risk stratification, and treatment patterns of atrial fibrillation in a Colombian population?
Observational (n=357)
What are the sociodemographic and clinical features, risk stratification, and treatment patterns of atrial fibrillation in a Colombian population?
In a Colombian cohort of atrial fibrillation patients, there is a high burden of thromboembolic risk, yet a significant proportion (24%) remain undertreated with anticoagulation.
Background: Atrial fibrillation (AF) is the most common type of cardiac arrhythmia worldwide. This study aimed to determine the sociodemographic and clinical features of AF in a Colombian population.Methods: An observational, retrospective study was conducted using a sample of patients diagnosed with AF. Electronic medical records were reviewed to determine specific sociodemographic, clinical, risk stratification, outcome, and pharmacological variables.Results: A total of 357 patients with a mean age of 69.4 ± 13.3 years were included; 52.4% (n = 187) were women. Most patients (84.0%; n = 300) had an elevated risk of thromboembolism and an indication for anticoagulation, but 72 (24.0%) of these patients did not receive such treatment. Among the patients, 23.2% had HAS-BLED scores ≥3. During the study period, 76 patients (21.3%) had 121 adverse events, of which 75.2% (n = 91) were any bleeding events (major, minor, etc.) and 24.8% (n = 30) were thrombosis events (i.e., stroke). At the end of the follow-up period, the number of prescriptions for direct anticoagulants had increased, and warfarin decreased.Conclusions: AF primarily affects Colombian adults >65 years old. A high burden of comorbidities and a risk of thromboembolism were found in most patients; however, lack of treatment was evident in a large percentage of cases.
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Medina-Morales et al. (2021) conducted an observational in Atrial fibrillation (n=357). Atrial fibrillation was evaluated on Adverse events (bleeding and thrombosis).
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