Fig 3. Caspase-3 activity in polyps in response to treatment with everolimus.Polyps collected before and after treatment were immunohistochemically stained for cleaved caspase-3 (active capsase-3) and counterstained with hematoxylin (in blue).The red arrows point to some of the cleaved caspase-3 positive cells (in brown).(A) Polyp tissue collected before treatment.(B) Polyps obtained after 6 months.(C) Polyps obtained after 8 months.Original magnification, ϫ20
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Klümpen et al. (2010) studied this question.
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