Drug Delivery and Hydrotropism

Drug delivery systems play major role in the utilization of drugs.The mode of injection of the drug plays a major role is deciding ease of drug delivery.For the pharmaceutical compounds, it is very important to have proper drug delivery system which will keep their effect intact during the transportation in side our body.The concentration of the drug inside the body needs to be maintained above certain value to get effect out of the drug.For this purpose, the drug intake is given three to four times a day to the patient.The ability of the person to follow the drug intake schedule and the severity of the drug requirement decides mode of drug delivery which in turn has major role to play in drug transportation.The solubility of the compound in the solvent plays important role in utilization of the compound for drug delivery.Many common drugs are injected into body by oral route through gastrointestinal tracts.Many of the drugs are susceptible to the enzymatic degradation and hence cannot be injected orally.Such drugs are administered through needles.Increasing solubility of the compound can be done by using surfactants, pH adjustments, size reduction, salt formation.Each method has some merits and demerits.Hydrotropism is one of the very useful method for increasing solubility of the drugs.