Adrenergic Beta-receptor Blockade and the Relationships between Physical Working Capacity, Heart Volume, and the Total Amount of Hemoglobin
Key result
Beta-blockade normalizes relationships between working capacity, heart volume, and hemoglobin in psychiatric patients.
- n=29
Why the study?
The relationships between physical working capacity, heart volume, and total hemoglobin vary widely in patients with psychiatric diseases, and the effect of adrenergic beta-receptor blockade on these relationships was unclear.
Does adrenergic beta-receptor blockade normalize the relationships between physical working capacity, heart volume, and total hemoglobin in patients with psychiatric diseases?
Population
29 patients with various psychiatric diseases
Comparison
Adrenergic beta-receptor blockade vs baseline and historical healthy subjects
Design
Observational study with intervention (beta-receptor blockade)
Authors
Discussion
Loading...
Member takes
Implication
May reflect variable hyperkinetic circulation in psychiatric patients; leaves open beta-blockade effects on these relationships.
Structured PICO
Does adrenergic beta-receptor blockade normalize the relationships between physical working capacity, heart volume, and total hemoglobin in patients with psychiatric diseases?
P
Population
29 patients with various psychiatric diseases.
I
Intervention
Adrenergic beta-receptor blockade
C
Comparator
Baseline (pre-blockade) and historical healthy subjects
O
Outcome
Relationships between physical working capacity, heart volume, and the total amount of hemoglobinsurrogate
Adrenergic beta-receptor blockade normalizes hyperkinetic circulation parameters in patients with psychiatric diseases.
Cite This Study
Curt Daniel Furberg (1967) studied various psychiatric diseases (n=29). adrenergic beta-receptor blockade vs. baseline / healthy subjects was evaluated on relationships between physical working capacity, heart volume and the total amount of hemoglobin. Adrenergic beta-receptor blockade markedly decreased deviations from regression lines for physical working capacity, heart volume, and total hemoglobin in patients with psychiatric diseases.