Evaluating the Efficacy of Bioceramic versus Resin-Based Sealers in Endodontic Treatments: A Comparative Analysis

Background: Root canal therapy relies heavily on the effectiveness of the sealer used to ensure successful treatment outcomes. Bioceramic and resin-based sealers are commonly employed, each offering distinct advantages and drawbacks. This study aimed to compare the effectiveness of bioceramic versus resin-based sealers in root canal therapy, focusing on microbial leakage, seal integrity, postoperative pain, and healing rates. Methods: A randomized controlled trial was conducted involving 120 patients who required root canal therapy. They were randomly assigned to receive either bioceramic or resin-based sealers. The primary outcomes were microbial leakage and seal integrity, evaluated through clinical and radiographic examinations. Secondary outcomes included postoperative pain and healing rates, monitored over a six-month follow-up period. Results: < 0.05). Additionally, patients in the bioceramic group reported significantly less postoperative pain. However, there were no significant differences in healing rates between the two groups. Conclusion: Bioceramic sealers demonstrate superior clinical outcomes in terms of microbial leakage prevention and seal integrity, suggesting that they may be more beneficial than resin-based sealers in root canal therapy. These findings support the use of bioceramic materials for improving patient outcomes in endodontic treatments.