13C NMR chemical shift substituent effects. 5—α‐Monosubstituted N,N‐diethylacetamides

Carbon‐13 NMR chemical shifts of a series of α‐monosubstituted N,N‐diethylacetamides [YCH2C(O)NEt2, Y = Me, Cl, Br, I, OMe, SMe, and NMe2] are reported. The α‐methylene and carbonyl carbon chemical shifts are correlated with the Pauling electronegativities (Ep) and Charton's localized electrical parameters (σL), respectively. The non‐equivalence of the chemical shifts for the syn and anti‐N‐alkyl carbon atoms are attributed to the electric field and steric compression effects and also to the YCH2cis and trans‐γ‐effects.