Key result
LIPA locus links post-GWAS findings to mechanistic insights and clinical translation in CAD.
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Positions LIPA as a translational model in CAD genetics; leaves open clinical adoption pending prospective validation.
From discovery to clinical applications: the intersting story of LIPA.
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Wild et al. (2025) studied this question. The LIPA gene locus serves as a paradigm for translating post-GWAS discoveries into mechanistic insights and clinical applications for coronary artery disease.
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