Blood group H antigen with globo-series structure, reacting with the monoclonal antibody MBrl, was isolated and characterized from human blood group O erythrocytes. The structure was identified by methylation analysis, direct probe mass spectrometry, and 1H-nuclear magnetic resonance spectroscopy as shown below: Fuc alpha 1----2Gal beta 1----3GalNAc beta 1----3Gal alpha 1----4Glc beta 1----1Cer.
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Kannagi et al. (1984) studied this question.
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