Whole plant of Urticadioica Linn. (Urticaceae) were subjected to extraction with different solvent according to polarity and further to obtain antioxidant rich extract. Different concentrations of different solvent extracts were subjected to antioxidant assay by DPPH, Nitric oxide NO scavenging method and Total phenolic contents. The IC50 values for different solvent extracts (Petroleum ether, ethyl acetate, n-butanol, ethanol) of Urticadioica Linn.(UD) were found to be 215.96 ± 0.066, 78.99 ± 0.171, 168.24 ± 0.346 and 302.90 ± 0.141 respectively in comparison to L-Ascorbic acid as standard with IC50 values of 26.24 ± 0.193 respectively in DPPH model.
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