Key result
Subthreshold stimulation mapping predicts successful ablation sites with up to 100% positive predictive value.
Why the study?
The predictive value of subthreshold stimulation for identifying optimal ablation sites in different types of reentrant supraventricular tachycardia was unclear.
Does subthreshold stimulation predict successful catheter ablation sites in patients with reentrant supraventricular tachycardia?
Observational (n=50)
No
Does subthreshold stimulation predict successful catheter ablation sites in patients with reentrant supraventricular tachycardia?
Subthreshold stimulation is a specific method that can help predict successful catheter ablation sites in patients with reentrant supraventricular tachycardia.
STS may guide ablation sites in AVNRT/AVRT without capture; leaves open prospective validation before clinical adoption.
The effects of subthreshold stimulation (STS) by direct current were investigated in 20 patients with atrioventricular nodal reentrant tachycardia (AVNRT), 27 with atrioventricular reentrant tachycardia (AVRT) and 3 with idiopathic atrial reentrant tachycardia (IART) STS was delivered to each eligible site for ablation prior to radiofrequency application. STS was defined as 'positive' if it could terminate the tachycardia or disrupt the conduction of accessory pathways without myocardial capture and defined as 'negative' if it could not. Radiofrequency ablation was performed irrespective of a positive or negative result from STS and was successful in all 50 patients. Among the 50 successful ablation sites, STS was positive at 26 sites (11 sites in AVNRT, 12 in AVRT and 3 in IART). STS was positive at 4 sites where ablation failed in 3 patients with AVRT and was negative at 8 sites where ablation was successful in 4 patients with AVNRT and 4 with AVRT. The positive and negative predictive value of STS for the detection of the optimal ablation site were, respectively, 100% and 74% in AVNRT, 73% and 72% in AVRT, and both 100% in IART STS-guided mapping is a specific method to predict the successful catheter ablation of reentrant supraventricular tachycardia.
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Ueda et al. (2001) conducted an observational in Reentrant supraventricular tachycardia (n=50). Subthreshold stimulation (STS) was evaluated on Positive predictive value of STS for successful ablation site. Subthreshold stimulation-guided mapping predicted successful catheter ablation sites with a positive predictive value of 100% in AVNRT and IART, and 73% in AVRT.
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