A case of erythema multiforme major with multiple mucosal involvements in COVID‐19 infection

A case of erythema multiforme major with multiple mucosal involvements in COVID-19 infection Dear Editor, Coronavirus disease 2019 (COVID-19) is a pandemic infection owing to the Severe Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) that, in the worst case, can lead to fatal acute respiratory distress syndrome. It was first identified in hospitalized patients in Wuhan, China, in December 2019 and January 2020. 1 Since the start of the COVID-19 epidemic, many clinical manifestations have been described outside of the respiratory tract, most of which are thought to be caused by inflammation and deleterious immune responses to the virus. To date, several dermatological manifestations have been described during COVID-19: petechial rash, erythematous rash, varicella-like vesicles, urticarial eruption, 2,3 and livedo reticularis. Other dermatological manifestations of acral involvement have been published such as red-purple papules mimicking chilblains disease, acro-ischemia, and recently atypical erythema multiforme palmar plaques. 4 Cebeci F. et al. 5 first described the mucosal damage in COVID-19. Herein, we report on a case of severe and pure mucous damages in a COVID-19-positive inpatient. This case brings additional data implementing the knowledge on the dermatological signs during COVID-19.