PURPOSE AND APPROPRIATE SAMPLE TYPESThe 10-color panel consisting of 15 monoclonal antibodies (mAbs) is developed to detect leukemia and lymphoma cells in small cell samples [hypoplastic bone marrow (BM), fine needle aspirates, or cerebral spinal fluids (CSFs)].MAbs conjugates were selected to identify populations of distinct cell lineages and to determine stages of differentiation based on specific antigen expression patterns.As such, conjugates containing the same fluorochrome could be combined.This panel is tested on peripheral blood (PB), BM, and CSF and provides a strong improvement of diagnostic potential.
No takes yet. Share an insight, caveat, or question.
Preijers et al. (2012) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: