Key result
Post-COVID-19 presentation features extensive DVT, pulmonary embolism, and paradoxical thrombus in transit across a PFO.
Why the study?
The COVID-19 pandemic has led to a significant increase in thromboembolic illnesses, including complex cases involving large thrombi in transit across the foramen ovale that pose serious systemic embolism risks.
Case Report (n=1)
A large thrombus in transit across a patent foramen ovale in a patient with pulmonary embolism carries a serious risk of systemic thromboembolism and warrants urgent surgery, highlighting potential post-COVID thromboembolic complications.
Hemodynamically significant large pulmonary embolism causes right ventricular dysfunction that stretches open the foramen ovale in the atrial septum. Paradoxical embolism is common in patients with right ventricular dysfunction. While anticoagulation and thrombolysis are considered the treatment of choice in pulmonary embolism, a large thrombus in transit across the patent foramen ovale carries a serious risk of systemic thromboembolism and warrants urgent surgery. The recent coronavirus disease 2019 (COVID-19) pandemic has led to a significant increase in the incidence of thromboembolic illnesses. A patient acutely presented with deep vein thrombosis, pulmonary embolism, large thrombus in transit across the foramen ovale along with elevation of multiple inflammatory biomarkers that were suggestive of a possible post-COVID sequelae. Images and management strategies are discussed in this report.
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Sagar et al. (2021) conducted a case report in Pulmonary embolism, deep vein thrombosis, and thrombus in transit across patent foramen ovale (n=1). COVID-19 was evaluated. A suspected COVID-19 recovered patient presented with deep vein thrombosis, pulmonary embolism, and a large thrombus in transit across a patent foramen ovale.
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