Eosinophilic granulomatosis with polyangiitis (EGPA), previously called Churg−Strauss syndrome, is a small- to medium-sized systemic necrotizing vasculitis characterized by eosinophil-rich tissue infiltrates and granulomatous lesions. Eosinophilic granulomatosis with polyangiitis belongs to the larger subgroup of anti-neutrophil cytoplasm antibodies (ANCA)−associated vasculitides. However, EGPA is characterized by a distinct biological and clinical presentation when compared with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA).
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Doreille et al. (2021) studied this question.
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