Key result
Higher ascending and arch aortic plaque volume is linked to early mortality and neurological complications, but not stroke.
Why the study?
The correlation between atherosclerotic plaque volume of the ascending aorta and aortic arch with postoperative adverse events and the impact of different clamping techniques on these events was unclear.
Does the cumulative volume of calcified lesions of the aorta correlate with adverse postoperative events, and does the clamping technique affect outcomes in cardiac surgery?
Observational
Does the cumulative volume of calcified lesions of the aorta correlate with adverse postoperative events, and does the clamping technique affect outcomes in cardiac surgery?
The volume of calcified lesions in the ascending aorta and aortic arch is a predictor of early mortality, critical illness polyneuropathy/myopathy, and delirium in cardiac surgery patients, regardless of the clamping technique used.
Answers are grounded in this paper and cite their sources.
Aortic plaque volume may aid risk stratification for mortality and non-stroke complications in cardiac surgery; leaves open whether it should guide clamping or other interventions.
One of the major key questions raised in this retrospective study was to identify any correlation of atherosclerotic plaque volume of the ascending aorta and aortic arch with adverse events such as postoperative stroke, critical illness polyneuropathy and myopathy, as well as delirium and all-cause in-hospital mortality. In a second phase of this study, we investigated the relationship between atherosclerotic plaque volume and adverse events regarding the construction of proximal anastomosis on coronary artery bypass grafting procedures using different clamping techniques such as construction of anastomosis on cross-clamping or cross-clamping plus consecutive partial clamping of the aorta. The key findings of our research were that the size of calcium lesions of the ascending aorta and aortic arch correlates with early mortality, critical illness polyneuropathy/myopathy, and delirium but not with stroke. On the other hand, there were no significant differences between isolated cross-clamping versus cross-clamping plus consecutive partial clamping of the aorta regarding the primary adverse events by means of mean plaque volume.
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Ioannou et al. (2022) conducted an observational in Cardiac surgery. Atherosclerotic plaque volume of the ascending aorta and aortic arch was evaluated on Postoperative stroke, critical illness polyneuropathy and myopathy, delirium, and all-cause in-hospital mortality. Atherosclerotic plaque volume of the ascending aorta and aortic arch correlated with early mortality, critical illness polyneuropathy/myopathy, and delirium, but not with stroke.
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