Key result
Pericardial mesothelial cells govern post-injury healing and prevent adhesion formation.
Why the study?
The normal structure and functions of the pericardium are essential for correct healing after injury, but unfavorable resolution of pericarditis can lead to serious complications.
This review summarizes the structural and functional roles of the pericardium and its mesothelial cells in health, as well as the pathophysiological consequences of pericardial injury such as adhesions.
No takes yet. Share an insight, caveat, or question.
Mesothelial cells drive pericardial repair and inflammation; leaves open whether targeting them prevents post-pericarditis adhesions.
Jaworska-Wilczyńska et al. (2016) conducted a review in Pericardial structure and function. The normal structure and functions of the pericardium, particularly the mesothelial cells, determine correct healing after injury, whereas unfavorable resolution leads to adhesions.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: