Key result
The 1955 development of preparative ultracentrifugation by Havel, Eder, and Bragdon revolutionized lipoprotein analysis and laid the foundation for modern cardiovascular risk assessment.
Answers are grounded in this paper and cite their sources.
The 1956 Havel et al. paper established a foundational ultracentrifugation method for lipoprotein analysis that remained applicable for nearly 50 years.
In 1956, the JCI published a paper by Richard Havel, Howard Eder, and Joseph Bragdon on a method using an ultracentrifuge to physically separate plasma lipoproteins and chemical methods to analyze their lipid constituents. This paper has been much cited (7081 times as of this writing) in part because it represents a solid method that, with various modifications, has been applicable for the study of lipoproteins for almost half a century.
No takes yet. Share an insight, caveat, or question.
Scott M. Grundy (2004) conducted a review in Cardiovascular disease and lipoprotein metabolism. Lipoprotein analysis methods was evaluated. The 1955 development of preparative ultracentrifugation by Havel, Eder, and Bragdon revolutionized lipoprotein analysis and laid the foundation for modern cardiovascular risk assessment.
Synapse has enriched 10 related papers. Consider them for comparative context: