The role of synthetic biology in climate change mitigation

There is growing agreement that the aim of United Nations Framework Convention on Climate Change, which is to avoid dangerous anthropogenic interference with the climate system, is not likely to be met without inclusion of methods to physically remove atmospheric carbon. A number of approaches have been suggested, but the community appears to be silent on the potential of one of the most revolutionary technologies of the current century, systems and synthetic biology (SSB). The potential of SSB to modulate the fast carbon cycle, and thereby mitigate climate change is in itself enormous, but if the history of genomics is any measure, it is also reasonable to expect sizeable economic returns on any investment. More generally, the approach to climate control has been badly unbalanced. The last three decades have seen intense international attention to emission control, with no parallel plan to test, scale and implement carbon removal technologies, including attention to their economic, legal and ethical implications. REVIEWERS: This article was reviewed by Richard Roberts, Aristides Patrinos, and Eugene Koonin, all of whom were nominated by Itai Yanai. For the full reviews, please go to the Reviewers' comments section.