Incidence (1991~1993) and Survival Rates (1991-2003) of Retinoblastoma in Korea

Purpose To determine the incidence (1991∼1993) and survival rates (1991∼2003) of retinoblastoma in Korea. Methods Data of all Korean patients diagnosed with retinoblastoma from 1991–1993 were retrospectively collected by the hospital-based national registry based on notifications from physicians who are able to diagnose retinoblastoma. In addition, the clinical findings and prognostic factors associated with survival rate were analyzed. Results There were a total of 108 distinct patients diagnosed with retinoblastoma in the registry. The incidence of retinoblastoma in Korea was 4.99 per 100,000 childbirths, and the survival rate for 13 years (1991–2003) was 77.8%. The survival rate was significantly lower in the population of bilateral retinoblastoma patients, as compared to unilateral retinoblastoma patients. Optic nerve invasion was found to be an independent variable for the reduction of survival rate, although its effects were not significant. Conclusions In the present study, the incidence and survival rates of retinoblastoma in Korea were presented for the first time. The incidence rate was similar to rates reported from other countries. On the other hand, the survival rate was lower than those in European and the United States.