All articles of this category The synthesis of new 1,2-aminoalcohol derivatives 1b-d and 8a-h and their application in the stereoselective allylation of ethyl methyl ketones is described. The best results were obtained with the biphenyl derivative 8f , allowing the synthesis of tert -homoallylic ether 9f and 10f with a selectivity of 18:1. Allylation - Allylsilane - Homoallylic alcohol - Ephedrin - TMSOTf
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Tietze et al. (1996) studied this question.