Key result
The reward-only condition significantly increased oxyhemoglobin concentrations in the right ventrolateral prefrontal cortex compared with the punishment-only condition (p < 0.01).
Cross-Sectional (n=20)
Randomized crossover of conditions
No
Right ventrolateral prefrontal cortex activation is modulated differently by reward versus punishment incentives during motor inhibition tasks.
It is unclear whether behavioral inhibition leads to heightened brain activation in response to reward or punishment incentives. In this study, we utilized near-infrared spectroscopy (NIRS) to evaluate right ventrolateral prefrontal cortex (VLPFC) activity during a reward/punishment Go/No-go task. As hypothesized, the activation of the right VLPFC was modulated according to different incentive outcomes during the Go/No-go task. Under the reward-only condition, oxyhemoglobin (oxy-Hb) concentrations in the right VLPFC significantly increased as compared with those under the punishment-only condition. In addition, the percentage of commission errors under the punishment-only condition was negatively correlated with neuroticism. These results provide new evidence that the role of the right VLPFC is modulated according to the reward/penalty outcomes, and the relation between motor inhibition and personality traits.
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Masui et al. (2009) conducted a cross-sectional in Healthy volunteers (n=20). Reward-only condition (RR) vs. Punishment-only condition (PP) was evaluated on Oxyhemoglobin (oxy-Hb) concentration in the right ventrolateral prefrontal cortex (VLPFC) (p=<0.01). The reward-only condition significantly increased oxyhemoglobin concentrations in the right ventrolateral prefrontal cortex compared with the punishment-only condition (p < 0.01).
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