Mycotic Meningitis Due to Candida

The clinical history and necropsy findings are presented of a patient who died with central nervous system involvement of an obscure nature. At necropsy the appearance of the lesion suggested tuberculous meningitis. However, microscopic examination revealed the presence of, and the reaction to, a fungus of the genus Candida, probably Candida albicans. The case is presented because Candida is a rare cause of meningitis. Smith and Sano and Miale have reported instances of meningeal involvement by Candida albicans. This however is the first case in which localization occurred in the central nervous system only. REPORT OF CASE L. J., a Negro aged 25, was first seen at the University Hospitals on Sept. 1, 1941, when he complained of headache of eleven months' duration. The pain was bitemporal with the sensation of the eyes "drawing." Four months prior to admission his neck became painful and diplopia developed. Two weeks before admission