Key result
An ectopic expression system in Xenopus oocytes successfully identified one monoclonal antibody (K1C3) that exclusively recognized the RCK1-protein isoform without cross-reactivity.
An ectopic expression system in Xenopus oocytes successfully enabled the selection of a monoclonal antibody specific to the RCK1 potassium channel isoform.
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RCK1-specific monoclonal antibodies advance channel research tools; leaves open any cardiovascular diagnostic or therapeutic roles pending validation.
Reinhardt-Maelicke et al. (1993) studied this question. Ectopic expression system in Xenopus oocytes was evaluated on Selection of RCK1 isoform-specific antibodies. An ectopic expression system in Xenopus oocytes successfully identified one monoclonal antibody (K1C3) that exclusively recognized the RCK1-protein isoform without cross-reactivity.
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