Current Medical Therapy for Non-infectious Uveitis and Ocular Inflammatory Disease

Current Medical Therapy for Non-infectious Uveitis and Ocular Inflammatory DiseaseUveitis is an inflammatory eye disease affecting the iris, ciliary body, and choroid that can lead to symptoms ranging from redness, pain, and blurred vision to markedly diminished acuity in the setting of severe or chronic disease. 1 It affects approximately 38,000 Americans per year, with an incidence of 15 cases per 100,000 per year and a prevalence in the US and Europe of 38 per 100,000. 2 The broad disease entity of uveitis can be further classified into the anatomical divisions of anterior, intermediate, posterior, and panuveitis. 2 Anterior uveitis primarily affects the iris, ciliary body, cornea, or sclera, and usually has a non-infectious-and often idiopathic-etiology. 1 Overall, anterior uveitis is the most common form, representing 28-61% of all cases. 2 Intermediate uveitis affects the anterior vitreous and pars plana, causing floaters and vision loss from cystoid macular edema. 1 Intermediate