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The progressive introduction of inosinic residues into the poly A chain results in: (a) The disappearance of the characteristic structural transition of poly A at acid pH's. (b) A fall in helical content, as measured by ultraviolet hypochromism and optical rotation. (c) A lowering of the melting point of the complex with poly U. (Author)
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Robert Frank Steiner (1961) studied this question.
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