Key result
Early neonatal treatment for cardiac intrapericardial teratoma is linked to ~71% survival.
Why the study?
Early treatment strategies and outcomes of cardiac intrapericardial teratoma in newborns were not comprehensively summarized in recent literature.
What are the clinical characteristics and outcomes of newborns with cardiac intrapericardial teratoma treated in the neonatal period?
Systematic Review (n=38)
What are the clinical characteristics and outcomes of newborns with cardiac intrapericardial teratoma treated in the neonatal period?
Intrapericardial teratoma in newborns generally has a good prognosis without the need for intrauterine procedures, though hydrops with hemodynamic impairment is associated with mortality.
Early surgery for neonatal cardiac IPT without hydrops may yield good outcomes; leaves open optimal selection and timing criteria.
OBJECTIVE: To present a case of an early treatment of cardiac intraperitoneal teratoma (IPT) in a newborn and its associated systematic literature review. METHODS: We presented a case of a newborn with IPT but without hydrops and having a good perinatal outcome after cardiac surgery. Using the PubMed database, we conducted a systematic literature review of articles regarding cases with cardiac IPT diagnosed and treated in the neonatal period and published in English from 2004 onward. We excluded cases that involved fetal death or interrupted gestation events. RESULTS: In total, 38 cases of IPT from 31 articles were included. The mean ± standard deviation of the gestational age at diagnosis and delivery were 27.9 ± 5.7 and 33.0 ± 3.5 weeks, respectively, and that of birth weight was 2373 ± 834.5 g. The majority of fetuses (42.1%) were males. Pericardial effusion was the most common symptom (60.5%) followed by hydrops (42.1%) and respiratory distress (42.1%). Intrauterine procedure was not performed in 63.1% of cases, and 71.0% of newborns were alive. CONCLUSIONS: IPT in newborns is usually associated with a good prognosis without the need for intrauterine procedures. Cases with IPT-related death are associated with hemodynamic impairment in fetuses with hydrops.
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Cavalcante et al. (2018) conducted a systematic review in Cardiac intrapericardial teratoma (IPT) (n=38). Early treatment was evaluated on Survival. Early treatment of cardiac intrapericardial teratoma in newborns was associated with a 71.0% survival rate, with 63.1% of cases not requiring intrauterine procedures.
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