Helicobacter pylori Eradication in Gastric: Mucosa-Associated Lymphoid: Tissue Lymphomas

Letters15 January 1996Helicobacter pylori Eradication in Gastric: Mucosa-Associated Lymphoid: Tissue LymphomasCarlos Montalban, MD, Daniel Boixeda, MD, and Carmen Bellas, MDCarlos Montalban, MDHospital Ramon y Cajal; Madrid, Spain, Daniel Boixeda, MDHospital Ramon y Cajal; Madrid, Spain, and Carmen Bellas, MDHospital Ramon y Cajal; Madrid, SpainAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-124-2-199601150-00023 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We read with interest the article by Roggero and coworkers [1] showing that eradication of Helicobacter pylori can induce regression of localized low-grade gastric mucosa-associated lymphoid tissue (MALT) lymphoma. Their finding of histologic remission in 60% of the patients confirm the results Wotherspoon and colleagues found in a small series [2]. Roggero and colleagues also found that regression was a progressive process in 8 of their 15 patients. Clinical and histologic regression of low-grade MALT lymphoma is the first goal of therapy. However, more accurate molecular studies are needed to show cure with eradication of latent residual ...References1. Roggero E, Zucca E, Pinnotti G, Pascarella A, Capella C, Savio A, et al. Eradication of Helicobacter pylori infection in primary low-grade gastric lymphoma of mucosa-associated lymphoid tissue. Ann Intern Med. 1995; 122:767-9. Google Scholar2. Wotherspoon AC, Doglioni C, Diss TC, Pan L, Moschini A, de Boni M, et al. Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori. Lancet. 1993; 342:575-7. Google Scholar3. Montalban C, Manzanal A, Boixeda D, Redondo C, Bellas C. Treatment of low-grade gastric MALT lymphoma with Helicobacter pylori eradication. Lancet. 1995; 345:798-9. Google Scholar4. Wotherspoon AC, Doglioni C, de Boni M, Spencer JO, Isaacson P. Antibiotic treatment for low-grade gastric MALT lymphoma. Lancet. 1994; 343:1503. Google Scholar5. Montalban C, Castrillo JM, Abraira V, et al. Gastric B-cell mucosa-associated lymphoid tissue (MALT) lymphoma. Clinicopathological study and evaluation of the prognostic factors in 143 patients. Ann Oncol. 1995; 6:355-62. Google Scholar Author, Article, and Disclosure InformationAffiliations: Hospital Ramon y Cajal; Madrid, Spain PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInvolved-site radiotherapy for Helicobacter pylori –independent gastric MALT lymphoma: 26 years of experience with 178 patientsHelicobacter pylori Strains and Gastric MALT LymphomaThe role of Helicobacter pylori infection in hematological disordersFrom the Alps to Sicily: A panorama of Italian lymphomasEvolving Role of Radiation Therapy for Hematologic MalignanciesSerum Antibody Responses to Helicobacter pylori and the cagA Marker in Patients with Mucosa-Associated Lymphoid Tissue Lymphoma 15 January 1996Volume 124, Issue 2Page: 275KeywordsB cellsChemotherapyHelicobacter pyloriLymphoid tissueLymphomaMALT lymphomaPolymerase chain reactionSurgery ePublished: 15 August 2000 Issue Published: 15 January 1996 Copyright & PermissionsCopyright © 1996 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...