plastic cells are all consistent with the disease as it has been described in humans and dogs. The clinical presentation in this case is unique because it centers around the involvement of bone marrow rather than the central nervous system. Additionally, the vast majority of cases that have been examined in humans and the few in dogs have expressed cell markers of either B or T lymphocytes. Although definitive immunohistochemical characterization of lymphocyte type was not accomplished, the current case appears to have neoplastic cells originating from poorly or undifferentiated lymphoid cells that prior to malignant transformation had not developed the capability to express those antigens examined in this report.
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Rochat et al. (1996) studied this question.
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