Mechanical Thrombectomy for Post-Thrombotic Venous Obstruction is Associated with Venous Wound Healing

OBJECTIVE: To evaluate the association between mechanical thrombectomy (MT)-combined with standard wound care and adjunctive endovenous interventions, as indicated-and venous wound healing in patients with post-thrombotic venous obstruction. METHODS: This multicenter, retrospective analysis included adults with venous wounds secondary to lower extremity deep vein thrombosis (DVT). MT was performed with one or more of the following devices (Stryker, Irvine, CA): ClotTriever System, ClotTriever BOLD catheter, or VenaCore catheter in native vessels, or RevCore catheter within occluded stents. Adjunctive venoplasty and stenting were performed as indicated. Standard wound care continued until wound healing or latest follow-up. Technical success was defined as crossing the lesion and deploying the study device; clinical success as any decrease from baseline in wound area. CONCLUSIONS: In this multicenter retrospective analysis, all patients with post-thrombotic venous wounds were healed or healing at latest follow-up after MT, with a 91% mean per-wound area reduction. These findings suggest that MT-combined with standard wound care and adjunctive endovenous interventions as indicated-may play an important role in treating recalcitrant post-thrombotic venous wounds.