The Changing Paradigm of Sepsis: Early Diagnosis, Early Antibiotics, Early Pressors, and Early Adjuvant Treatment*

Division of Pulmonary and Critical Care Medicine, Eastern Virginia Medical School, Norfolk, VA Division of Pulmonary and Critical Care Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT *See also p. 1592. Dr. Marik disclosed off-label product use of vitamin C for sepsis. Dr. Farkas has disclosed that he does not have any potential conflicts of interest.