Key result
An article by Ledwell and Aldrich provides significant insights into the gating mechanism of the voltage-dependent Shaker K channel.
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Highlights new findings on the gating mechanism of the voltage-dependent Shaker K channel.
Opening the Shaker K channel should be easy. Release the membrane potential that normally holds it closed, and massive stored molecular energies snap it rapidly and inexorably into its open configuration. Unlocking the inner secrets of this voltage-dependent channel's gating mechanism has proven to be much more difficult. An article by Ledwell and Aldrich in this issue has opened that door significantly.
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Joseph B. Patlak (1999) reported an editorial. An article by Ledwell and Aldrich provides significant insights into the gating mechanism of the voltage-dependent Shaker K channel.
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