Key result
Hip fracture surgery performed between 24 and 48 hours significantly increased the risk of one-year mortality by 3.88-fold compared to surgery within 24 hours in elderly patients.
Why the study?
Does hip fracture surgery within 24 hours reduce one-year mortality compared to surgery between 24-48 hours in elderly patients?
Cohort (n=212)
No
Does hip fracture surgery within 24 hours reduce one-year mortality compared to surgery between 24-48 hours in elderly patients?
Hazard Ratio: 3.88 (95% CI 1.67–9.02)
Absolute Event Rate: 25.47% vs 8.49%
p-value: p=0.002
In elderly patients with hip fractures, delaying surgery beyond 24 hours is associated with a nearly four-fold increased risk of one-year mortality.
Supports prioritizing surgery within 24 hours; observational data leave open whether RCTs would confirm mortality reduction.
Purpose: This study compared one-year survival rates between elderly patients who underwent hip fracture surgery within 24 hours versus those between 24–48 hours, and assessed factors influencing survival. Methods: This retrospective cohort study included elderly patients who underwent hip fracture surgery at Yasothon Hospital between June 1, 2019, and January 31, 2023. Patients were followed up until their final life status, as determined on January 31, 2024. In total, 212 patients were included, with 106 each undergoing surgery within 24 hours and between 24–48 hours. Statistical analyses were performed using the log-rank test and Cox regression. Results: A total of 36 patients (16.98%) died during the one-year follow-up period, with most deaths occurring in the 24–48-hour surgery group (27 patients, 25.47%). The mortality rates at 3 months, 6 months, and 1 year were 5.19%, 3.30%, and 8.49%, respectively. Significant mortality predictors included: age (adjusted HR = 1.06, 95% CI = 1.01–1.12); ASA class 3 (adjusted HR = 8.17, 95% CI = 1.03–64.79); general anesthesia (adjusted HR = 3.10, 95% CI = 1.46–6.57); complications (adjusted HR = 2.16, 95% CI = 1.02–4.56); and surgery performed after 24 hours (adjusted HR = 3.88, 95% CI = 1.67–9.02). Conclusions: Hip fracture surgery performed after 24 hours significantly increases the mortality risk in elderly patients. General anesthesia and postoperative complications are the key factors affecting survival. These findings emphasize the importance of surgery within 24 hours to reduce both mortality and complications in elderly patients.
No takes yet. Share an insight, caveat, or question.
A 2025 study conducted a cohort in Hip fracture (n=212). Hip fracture surgery between 24-48 hours vs. Hip fracture surgery within 24 hours was evaluated on One-year mortality (HR 3.88, 95% CI 1.67-9.02, p=0.002). Hip fracture surgery performed between 24 and 48 hours significantly increased the risk of one-year mortality by 3.88-fold compared to surgery within 24 hours in elderly patients.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: