Chirality switch up: A novel strategy has been developed to give optically pure fluorinated indolines with one or two stereogenic centers (see scheme; AN=nucleophilic addition, PG=protecting group, SNAr=intramolecular nucleophilic aromatic substitution, Tol=tolyl). Almost complete stereoselectivity and mild reaction conditions are the key features of the title reaction.
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Ruano et al. (2008) studied this question.