Key result
Aggressive immunosuppressive therapy resolves severe vocal cord paralysis after 18 months in juvenile dermatomyositis.
Why the study?
Sudden cardiac death is the leading medical cause of death during exercise, and routine cardiac assessment of professional footballers is needed to improve management and player safety.
Case Report (n=1)
Routine cardiac screening in professional footballers reveals a high proportion (9%) of 'grey screen' findings that are clinically challenging to differentiate from physiological adaptation.
Hypothesis-generating for immunosuppression in juvenile dermatomyositis vocal cord dysfunction; prospective studies needed before clinical adoption.
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ALTHAGAFI et al. (2013) conducted a case report in Juvenile Dermatomyositis with severe vocal cord dysfunction (n=1). Aggressive immunosuppressive therapy (corticosteroids, methotrexate, cyclophosphamide, IVIG, rituximab) was evaluated on Recovery of vocal cord motility. Aggressive immunosuppressive treatment led to complete recovery of bilateral vocal cord motility after 18 months in a 14-year-old boy with severe vocal cord dysfunction complicating juvenile dermatomyositis.
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