Key result
IV ceftriaxone shrinks a pericoronary pseudotumor caused by Helicobacter cinaedi by ~48%.
Why the study?
Cardiac tumors and tumor-like lesions are uncommon and most are true neoplasms, but tumor-like lesions caused by infections such as Helicobacter cinaedi are rarely reported.
Case Report (n=1)
Helicobacter cinaedi infection can present as a pericoronary pseudotumor that responds to targeted antibiotic therapy with ceftriaxone.
Answers are grounded in this paper and cite their sources.
May support targeted antibiotics for rare infectious pseudotumors; hypothesis-generating from single Level 5 case, needs prospective confirmation.
Cardiac tumors and tumor-like lesions are uncommon; most are true neoplasms. We here report a case of a pericoronary tumor-like lesion surrounding the right coronary artery in a 39-year-old man who presented with fever and chest pain. Although clarithromycin was administered for 1 week, his fever persisted. Helicobacter cinaedi (H. cinaedi) was isolated from blood cultures and found to be sensitive to ceftriaxone. A computed tomography scan showed a tumor-like lesion with no (18)F-fl uorodeoxyglucose uptake surrounding the right coronary artery. After administration of ceftriaxone, the tumor-like lesion diminished in size according to meticulous computed tomography examinations. We therefore concluded that it was caused by H. cinaedi infection. The patient has been followed up closely for 1 year and remains asymptomatic.
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Seto et al. (2014) conducted a case report in Pericoronary pseudotumor (n=1). Ceftriaxone was evaluated on Tumor size reduction. Intravenous ceftriaxone therapy reduced the size of a pericoronary pseudotumor caused by Helicobacter cinaedi by up to 48% in a 39-year-old man, who remained asymptomatic at 1-year follow-up.
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