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January 1, 1999Schizophrenia BulletinOpen Access

Tardive Dyskinesia: Possible Involvement of Free Radicals and Treatment With Vitamin E

Ahmed Elkashef Richard Jed Wyatt

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Abstract

A decade ago a hypothesis introduced to explain tardive dyskinesia (TD) implicated free radicals generated secondary to neuroleptic treatment. Since then many preclinical and clinical studies have investigated this possibility. These studies suggest that free radicals are probably involved in the pathogenesis of TD and that vitamin E could be efficacious in its treatment.

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Elkashef et al. (1999) studied this question.

synapsesocial.com/papers/6ab4a12ec00cd19ff64d3ba0 https://doi.org/10.1093/oxfordjournals.schbul.a033414

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