THE current interest in adrenal physiology encourages us to present a well documented case of Cushing's syndrome with certain instructive features. Whereas the diagnosis was made1 when the patient was first observed, it was later obscured by an x-ray induced remission. The response of the patient to subtotal resection of the adrenals was prompt and spectacular in contrast to previous failure of sustained remission after pituitary irradiation. A very satisfactory remission has followed the operation despite the absence of histologic proof of hyperplasia or hypertrophy of the adrenals.
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Kupperman et al. (1953) studied this question.
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