New developments in the non-thermal application of laser radiation in medicine are discussed. Tumour-seeking agents in combination with laser light are used for early tumour detection through fluorescence and for photodynamic therapy. Laser-induced fluorescence as well as Raman spectroscopy has potential for real-time monitoring of atherosclerotic plaques. Enhanced demarcation can be obtained by working in the time domain, which also opens up the new field of photon propagation studies in tissue. Work towards optical mammography is in progress in many laboratories. Finally, intense laser pulses can be used for generating x-ray radiation with interesting properties for enhanced medical imaging.
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Sune R. Svanberg (1997) studied this question.
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