Solid composites of calcium phosphates and hydroxypropylmethylcellulose (HPMC) were prepared at temperatures of 121 degrees C. Three biologically relevant calcium phosphates were studied: CaHPO(4). 2H(2)O (DCPD), calcium deficient apatite (CDA), and biphasic calcium phosphate (BCP). Properties of the solid composites obtained were studied with FTIR, X-ray diffraction, and SEM techniques. Special attention was devoted to seeking a possible chemical interaction between calcium phosphates and HPMC. No interaction was found. Thus, HPMC was proven to have no influence on chemical properties of calcium phosphates.
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Sergey V. Dorozhkin (2000) studied this question.
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