Key result
Neurofibromatosis is linked to coronary artery aneurysm and MI as a rare vascular manifestation.
Why the study?
Aneurysmal dilatation of coronary arteries as a vascular manifestation of neurofibromatosis is rarely reported and not well characterized.
Case Report (n=1)
Aneurysmal dilatation of the coronary arteries may be a rare vascular manifestation of neurofibromatosis.
Answers are grounded in this paper and cite their sources.
One case does not change practice; leaves open whether coronary aneurysms are a vascular manifestation of neurofibromatosis.
Aneurysms of the aorta, vertebral arteries, carotid artery, thyrocervical trunk, and mesenteric and celiac arteries have been described in patients with neurofibromatosis. These aneurysms may have part of the vessel wall replaced by neurofibromatosis tissue. One previous case reports a coronary artery aneurysm in a patient with neurofibromatosis who suffered a myocardial infarction due to thrombosis formation within the aneurysm. We document a second case of aneurysmal dilatation of a coronary artery in a patient with neurofibromatosis. This patient also had a myocardial infarction in a vascular distribution not involved by the aneurysm. The vascular changes associated with neurofibromatosis are reviewed. Aneurysmal dilatation of the coronary arteries may be a further vascular manifestation of this condition.
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Daly et al. (1992) conducted a case report in Neurofibromatosis (n=1). Neurofibromatosis was evaluated. A patient with neurofibromatosis developed a coronary artery aneurysm and myocardial infarction, suggesting coronary aneurysms may be a vascular manifestation of the condition.
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